Responsive Neurostimulation and the rise of real-time, personalized medicine

Danielle Gruber
10 min readNov 18, 2020

Nowadays, almost every item on the market can be personalized. Your feet are flat and you have tendonitis? There’s a shoe just for you. You’re a picky eater and need complete control over the toppings on your burrito bowl? Use the Chipotle app to select your preferred rice, beans, and veggies (I’m not sponsored by Chipotle, I just like burrito bowls).

But when it comes to medicine and health, we are lacking in the individualized approach department. Despite the incredible growth of technology over the past few decades, we don’t fully understand how different people develop diseases and respond to treatments. The traditional “one-size-fits-all” approach to medicine often misses the mark because each person’s biophysical constitution is unique.

While it may be easy enough to customize your burrito bowl, developing personalized treatments is a more complicated endeavor, especially in the case of neurological diseases. But, something that all patient-centric approaches have in common is that they are driven by data from you, the patient. Medical decisions are made on the basis of your unique characteristics, including molecular and behavioral biomarkers, rather than on population averages.

Fortunately, brain–computer interfaces (BCI) are paving the way for better, more specific patient care. BCI are a bidirectional communication pathway between an enhanced or wired brain and an external device, meaning the brain sends information to…

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Danielle Gruber

👋 I am a junior at Yale University majoring in electrical engineering. I’m interested in neuroscience, computer science, math, and everything in between!